
产品货号:
Z14070
中文名称:
DKK3抗体
英文名称:
Anti-DKK3 Antibody (N-term)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DKK3 Antibody (N-term) |
指标别名 | Dickkopf 3;Dickkopf related protein 3;Dkk 3;DKK3;hDkk 3;REIC;RIG |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | DKK3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This DKK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human DKK3. |
计算分子量 | 38kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | DKK3,like DKK1,DKK2,and DKK4,possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains,which are separated by a linker region and contain 10 cysteine residues each.The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane.The linker region contains 50 to 55 amino acids in DKK1,DKK2,and DKK4,whereas in DKK3 it contains only 12 amino acids.All DKKs have several potential sites for cleavage by furin-type proteases.Northern blot analysis revealed wide expression of the DKK3 transcript,with highest expression in heart,brain,and spinal cord.In situ hybridization reveals highest expression in mouse brain,eye,and heart. |
Uniprot ID | Q9UBP4 |
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